Optimization Lab
We’re redefining women’s health. The 15-minute appointments. The "everything looks great" dismissals. You deserve care that transforms the way you feel and show up in life. Welcome to OPTIMIZATION LAB— the industry's leading, completely personalized, data-driven women's preventative health clinic. Now accepting virtual appointments.
HEALTH
SOLUTIONS for
the MODERN
WOMAN
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OUR METHOD
oUR Method
Optimization Lab delivers advanced preventive care, turning comprehensive diagnostics into actionable insights.
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Precision Care For Women
Not just a pap smear and a mammogram. It’s the most complete women's health evaluation available, with 30+ advanced diagnostic tests utiliized.
Advanced Diagnostics
Evidence‑based, concierge‑level care
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Experts analyze your diagnostic data into a clear, personal plan, which you’ll review 1:1 with a physician
Actionable insights
Connection and Medical Excellence
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We translate deep diagnostics into a clear, personal plan. Expert guidance related to exercise, nutrition, hormone therapy and follow-up testing tailored to your individual needs.
expert-led execution
Optimization Plan Based In Science
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Find Where To Focus Your Effort
Whats
Aging You?
We're here to help! Take our 2-minute, science-backed quiz to uncover the real reason your energy, hormones, metabolism, or sleep feels off — and what to do about it.
Actually
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TAKE Control OF
YOUR Health TRANSFORM
Your life
2026 is the year you
WORK WITH ME
&
You're likely here for one of 3 reasons...
Biomedical literature grows by two scientific research articles every minute, 24 hours a day. In todays world you need a physician aligned with your goals, a scientist that understands and integrates ground breaking research as fast as it evolves, and data backed methods transforming you from yesterday's version into your winning version.
You’re an athlete or aspiring athlete who eats well, exercises consistently, and does “all the right things”, yet your body isn’t responding the way it used to.
You want real answers so your effort finally translates into results.
You’re ready to feel as capable in your body as you are in your life, with a plan that with your busy schedule instead of fighting it.
You’re a high-performing woman whose ambition hasn’t slowed down but your energy, sleep, and focus haven’t kept up. , with a plan that with your busy schedule instead of fighting it.
data driven, expert guidance so you can move forward with confidence
You’re a busy mother, business owner, CEO, or maybe all 3 whose done experimenting with DIY healthcare solutions. You’re ready for and quit second-guessing every move.
NOTHING MORE THAN
THE Action
NOTHING MORE THAN
OR
THE Action
NOTHING MORE THAN
Inaction
OR
THE Action
NOTHING MORE THAN
YOU TAKE TODAY.
Inaction
OR
THE Action
NOTHING MORE THAN
YOU TAKE TODAY.
Inaction
OR
THE Action
NOTHING MORE THAN
How well you live and what you will be able to do as you age is a function of
Nothing in life is guaranteed, least of all your health.
We are not Primary Care. Not a Med Spa, nor a one stop fits all Hormone Clinic. Optimization Lab is designed for women who want:
Call it Longevity Medicine. Call it Lifestyle Medicine. Call it what ever you'd like (except don't call it functional medicine). The is preventitive medicine, done differently. Out goal is to ensure the second half of your beautiful life equals, if not exceeds your first half.
- Medical oversight
- Deep Diagnostics
- Long-term partnership
- Personalized Care, not protocols
We're a strategic partner, not just a provider. Together we'll help you navigate the complex world of health optimization with clarity and confidence.
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Under The White Coat
When I'm not working you can find me...
As a painfully shy super nerd, I’m a lot more likely to be setting up an epic fort and enjoying movie night with my four kids than socializing at happy hour or a swanky party.
I got in-house detention in high school for writing an essay on how much my teacher sucked--bet I still got an A on the essay though! Heeeeey! Despite being a maverick and gifting my parents with premature grey hair, I earned a full-ride scholarship to Pennsylvania State Medical School.
I was named after my Great Grandmother and told my husband that my 1st child, whether it was a boy or a girl, would be named Charlie after my Great Grandfather the original Marie Sioussat's husband and one of my biggest sources inspirations.
Luckily, I married a man named Charlie so it was a non issue. I met my husband the first day of medical school...you should have seen him canvasing and shaking hands with everyone as they stood in line to register as if he was already gunning for class president. He is the worst gift-giver, but undeniably the best husband, father, and partner I could ever imagine.
BATTLING my kids in a an epic dance off, BUILDING or DIYing something in my home, or TENDING to my garden.
"Dr. Sioussat made me the most personalized and customizable treatment plan, based on my needs! She's helped me in ways no other doctor has ever even thought of."
Mona Camacci
Emily Cowlett
Chuck Sandlin
Trusted By 1000+ Patients and Pirates Like You
“Marie’s unique skill fusing medical research with actual application will help anyone who wants to get to that next level.”
"Dr. Sioussat is a a damn good doctor! That's all there is to say. Her knowledge and genuine desire to help people are worth their weight in gold."
If you're ready to finally bet on yourself, future-proof your health, & prove that
2026
If any of that rings true for you, you're in the right place, and you're right on time.
Explore whether Optimization Lab is the right fit.
You're anxious that no matter what you try, you’ll still feel stuck in a body that no longer feels like yours...
You’re worried that stress, lack of sleep and years of putting everyone else first have done permanent damage you can’t undo...
you don’t know where to start to reclaim your health, confidence, and sense of self — without sacrificing your career, your family, or your sanity...
You’ve mastered complex systems at work but your own body feels like the one problem you can’t solve...
You’re tired of being told to “just eat less” or “try harder,” when you’re already exhausted and doing everything...
you're wondering if this is just the price of getting older and question whether you’ve missed the window to feel strong, confident, and energized again...
Health and longevity can not be possessed & sold, only earned. I love the process of helping my clients appreciate & optimize the one beautiful life and body we were given.
IF YOu want:
Comprehensive analysis beyond standard labs. We dig deeper into your biochemistry, hormones, metabolism, and genetics to uncover what's really happening.
Evidence-based solutions for women's bodies. Healthcare research has historically centered on men. We focus on what actually works for women's unique physiology.
Integration of cutting-edge science and time-tested wisdom - We combine the best of conventional medicine, functional approaches, and emerging research.
A strategic partner, not just a provider. We're in your corner, helping you navigate the complex world of health optimization with clarity and confidence.
this is for you.
OPTIMIZATION LAB
WANT IN?
Science-backed. Physician-led. Designed for women like you who want more.